Shoichet lab toronto. She currently leads a laboratory of 25 and has graduated 148 researchers. My research focuses on the co-delivery of neural stem cells with ChABC and other pro-regenerative peptides to promote neuron regeneration after SCI. Improving blood supply in the ischemic region is critical for restoring myocardial function and prolonging survival. Feature of the Month: June/July 2016 Congratulations! Leah Kesselman, Irja Elliott Donaghue, and Malgosia Pakulska celebrate after convocation with Molly Shoichet. 1021/acsmaterialsau. Bahlmann, L. Education. Lia Huo PhD, 07/2025 Currently: Medical Student, University of Toronto Jonathan Labriola Post-Doctoral Fellow 04/2022 – 04/2025 Currently: Research Associate, University of Toronto Daniela Issacs-Bernal PhD, 04/2025 Currently: Research Engineer, Ripple Therapeutics, Inc. View Xiang Olivia Li’s profile on LinkedIn, a professional community of 1 billion members. Molly Shoichet is an expert in the study of polymers for drug delivery and tissue regeneration. 122818 Publication Please join me in congratulating Nicole Blaine on successfully defending her MASc! We’d also like to double-congratulate Ellie Monroe on her two presentation awards: Winning the Donnelly Centre UG best podium presentation; and winning the UnERD 2nd prize podium presentation. Jeremy Sivak on this research. 202010674 304. Dr. Shoichet MS. Project Approximately 750,000 vitrectomies are performed each year to treat various conditions including retinal detachment, macular hole, diabetic retinopathy, and cytomegalovirus retinitis. Smith, Prof. actbio. She has published over 530 papers, patents and abstracts and has given over 325 lectures worldwide. The latest, AmacaThera Yuan Yao Post-Doctoral Fellow, 09/2022 - PresentSiewan Prev 1 2 3 4 5 … 7 Next A Biomanufacturing Hub Network (BioHubNet) team led by U of T University Professor Molly Shoichet and Scientific Director of PRiME Next-Generation Precision Medicine, along with co-leads Gilbert Walker, Professor of Chemistry at U of T, and Darius Rackus, Assistant Professor of Chemistry and Biology at Toronto Metropolitan University, has been awarded $18. 2010 “Polymer scaffolds for biomaterials applications” Macromolecules, 43: 581-91 Molly co-founded AmacaThera in 2016 and is a University Professor at the University of Toronto, where her research focuses on drug and cell delivery strategies in the central nervous system (brain, spinal cord and retina) and 3D hydrogel culture systems to model cancer. Education Ph. 2010674: 1-32; doi: 10. 1186/s13287-024-03679-3 Publication Researchers from the Institute of Biomedical Engineering and Chemical Engineering at the University of Toronto have developed a novel method to dramatically extend the duration of glaucoma treatment. Molly Shoichet, Professor, University of Toronto; Canada Research Chair, Tissue Engineering Molly Shoichet is an expert in the study of polymers for drug delivery and tissue regeneration. Ballios BG; Kahlili S; Shoichet MS; van der Kooy D. • CBC News • University of Toronto Engineering News • Canadian Geographic Barry O' Sullivan News Contact Home People Molly Shoichet The Team Former Team Members Undergraduate Research SiewanCopyright © 2025 - WordPress Theme by CreativeThemes Video Format If your post contains video, please use this format. C. 1995 “The use of polymers in the treatment of neurological disorders” Trends in Polymer Science 3: 374-80 (Invited Education MASc Student (2025-present) Biomedical Engineering University of Toronto Bachelor of Science (2019-2024) Biochemistry The University of British Columbia Awards Ontario Graduate Scholarship (OGS) “Immunomodulation with local, sustained delivery of pituitary adenylate cyclase activating polypeptide results in improved functional recovery in stroke-injured mice” Research Assistant | Shoichet Lab · Experience: University of Toronto · Education: University of Toronto · Location: Toronto · 500+ connections on LinkedIn. She is focused on enhancing the cell-material interaction through controlled polymer chemistry and engineering. I ensure that our laboratory runs safely, smoothly and efficiently. 9 million in federal funding from the Publication “Engineering hydrogels for affinity-based release of therapeutic proteins” Teal, C. The Shoichet lab seeks to discover chemical reagents that can illuminate biological problems. I developed new protein therapeutic delivery mechanisms for controlled protein release. Select Video format in the appeared metabox and add the embed code from the video hosting you use (youtube, vimeo etc) Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Letko Khait, N. 1002/adfm. Molly Shoichet Project. These procedures involve removal of the vitreous gel that occupies the space between the lens and retina, followed by replacement with a substitute material. S. Jan 31, 2025 · Shoichet’s lab collaborated with Dr. Publication “Hyaluronan improves photoreceptor differentiation and maturation in human retinal organoids” Kawai K; Ho MT; Ueno Y; Adbo D; Xue C; Nonaka H; Nishida H; Honma Y; Wallace VA; Shoichet MS. 202403701 Publication “Redesigned Chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in the stroke-injured rat brain” Letko Khait N; Zuccaro S; Abdo D; Cui H; Siu R; Ho E; Morshead CM; Shoichet MS. 4c05176 “Transplanted human photoreceptors transfer cytoplasmic material but not to the recipient mouse retina” Ho MT; Kawai K; Abdo D; Comanita L; Ortin-Martinez A; Ueno Y; Tsao E; Rastgar-Moghadam A; Xue C; Cui H; Wallace VA; Shoichet MS. ca - Homepage polymers biomaterials tissue engineering drug delivery Articles 1–20 “Hydrogel assisted photoreceptor delivery inhibits material transfer” Ho MT; Ortin-Martinez A; Yan NE; Comanita L; Gurdita A; Pham Truong V; Cui H; Wallace VA Contact Home People Molly Shoichet The Team Former Team Members Undergraduate Research L. 3c02242 Publication Contact Home People Molly Shoichet The Team Former Team Members Undergraduate Research “Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels” Bahlmann LC; Xue C; Chin AA; Lu J; Thériault B; Uehling D; Yerofeyeva Y; Peters R; Liu K; Chen J; Martel AL; Yaffe M; Al-awar R; Goswami RS; Ylanko J; Andrews DW; Kuruvilla J; Laister RC; Shoichet MS. PhD Student (2023 – Present) Institute of Biomedical Engineering University of Toronto. 305. Candidate (2024-present) Chemical Engineering and Applied Chemistry University of Toronto Bachelor of Science, Honours (2020 – 2024) Biochemistry and Human Biology, minor in Immunology University of Toronto Project Retinitis pigmentosa (RP) is the most common hereditary retinal degenerative disorder, leading to vision loss. MORE Barry O' Sullivan. Two ongoing projects are 1. 1016/j. She is also a serial entrepreneur who has launched three companies. Shoichet eling cancer cell migration to better understand mechanisms Institute of Biomaterials and Biomedical Engineering University of Toronto of metastasis to treat disease; however, recapitulation of the Toronto, ON M5S 3G9, Canada tumor niche is a complex, iterative process that requires stra-E-mail: molly. Videos you watch may be added to the TV's watch history and influence TV recommendations. 1002/adma. In the article, Dr. 2025 Langmuir, special issue on “Pioneers in Applied and Fundamental Interfacial Chemistry: Shaoyi Jiang”, 41: 7174-7190; doi: 10. Professor Shoichet was recruited to the faculty at the University of Toronto in 1995 with a NSERC University Faculty Award, after completing her S. Transplantation of endothelial cells for therapeutic angiogenesis is promising for producing angiogenic cytokines and promoting revascularization. While protein-based therapeutic delivery to the retina has shown potential in delaying the onset of blindness, off-target effects and rapid drug clearance are significant barriers to success. My field of research encompassed polymer chemistry, biomaterials, and biochemical engineering. She currently leads a laboratory of 30 and has University of Toronto Master of Science (2014 – 2016) Pharmacology and Drug Development Tufts University School of Medicine Bachelor of Science (2007 – 2012) Harbin Medical University Awards Ontario Graduate Scholarship (OGS) 2020-2021 NSERC PROMOTE Award, McGill University 2019-2022 Cecil Yip Doctoral Research Award 2020-2021 Researchers from the Institute of Biomedical Engineering and Chemical Engineering at the University of Toronto have developed a novel method to dramatically extend the duration of glaucoma treatment. Prati Fabio Professor of Organic Chemistry Costi Maria Paola Medicinal chemistry professor University of Modena and Reggio Emilia Peter Gmeiner Friedrich-Alexander Universität Erlangen-Nürnberg Molly shoichet University of Toronto Andrej Sali University of California, San Francisco Jul 28, 2022 · A team of U of T Engineering researchers, led by Professor Molly Shoichet (ChemE, BME, Donnelly), has designed a new way to grow cells in a laboratory that enables them to better emulate cancerous tumours. I work closely with all the researchers in the cell and tissue culture facility. Applying these to G-Protein Coupled Receptors (GPCRs), which Excellence in teaching award (2013) Publications Hettiaratchi M, O’Meara M, O’Meara T, Pickering A, Letko Khait N, Shoichet M, “Re-Engineering Biocatalysts: Computational Redesign of Chondroitinase ABC Improves Efficacy and Stability”, Science Advances, 2020. 2023 ACS Materials AU (special issue), 3: 514-527; doi: 10. In light of these poor translational avenues, we are developing a local Project Retinal degenerative diseases, such as retinitis pigmentosa, are among some of the leading causes of vision loss. Shoichet MS; Rein DH. langmuir. Jose Moran-Mirabal Awards NSERC PROMOTE Award, McGill University 2022-2025 To overcome these issues, my project aims to develop chemically defined materials to differentiate liver cells and accelerate their clinical translation. Siewan Team Shumaim Barooj PhD Candidate, 2024 - Present Siewan Team Siewan Chan Administrative Assistant to Dr. Advanced Science “Acid-responsive polymer additives increase RNA transfection from lipid nanoparticles” Cheung TH; Fuchs A; Shoichet MS. J. There is a growing need for development of a Education PhD Student (2022 – Present) University of Toronto Chemical Engineering and Applied Chemistry Honours Bachelor of Science (2018-2022) Chemical Biology McMaster University Thesis Supervisor: Dr. ca tegic design to In science, you could say that Molly Shoichet has done it all. While the laboratory is pursuing a diversity of projects, they are linked by the common theme of polymeric design for medical application. 2024 , Stem Cell Research & Therapy, 15:79; doi: 10. Publication “Colloid-forming prodrug-hydrogel composite prolongs lower intraocular pressure in rodent eyes after subconjunctival injection” Dang M; Slaughter KV; Cui H; Jiang C; Zhou L; Mathew DJ; Sivak JM; Shoichet MS. Olsen & Paula T. In faucibus, risus eu volutpat pellentesque, massa felis feugiat velit, nec mattis… More Category 2 July 23, 2012 “Redesigned Chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in the stroke-injured rat brain” Letko Khait N; Zuccaro S; Abdo D; Cui H; Siu R; Ho E; Morshead CM; Shoichet MS. Her work includes tissue and polymer engineering, focusing on drug delivery and tissue regeneration. D Student (2020 – Present) Chemical Engineering and Applied Chemistry Unviersity of Toronto Bachelor of Applied Science (2013-2018) Nanotechnology Engineering University of Waterloo Molly Shoichet is an expert in the study of polymers for drug delivery and tissue regeneration. Shoichet MS; Gentile FT; Winn SR. WELCOME TO THE SHOICHET LAB “Our research program requires a cross disciplinary approach where aspects of engineering, chemistry, and biology are applied to the fields of Regenerative Medicine, Tissue Engineering and Drug Delivery. 1995 “The use of polymers in the treatment of neurological disorders” Trends in Polymer Science 3: 374-80 (Invited Project I am the head technician in the Shoichet research laboratory. Department of Chemical Engineering and Applied Chemistry University of Toronto Doctor of Philosophy (2016 – 2022) Department of Chemical Engineering Massachusetts Institute of Technology Supervisors: Bradley D. Our article, “Long-Acting Ocular Injectables: Are we Looking in the Right Direction?,” has been selected and included in the 10th Anniversary Special Collection of Advanced Science. 1016/0142-9612 (96)85566-9 1995 50. 2023 Publication Smith LJ; Skirzynska A; Chin AA; Arnold AE; Kushida M; Dirks P; Shoichet MS. 1016 Publication Yui Ueno Visiting Scientist, 06/2022 - Present Siewan 1 2 Next PhD Candidate in Chemical Engineering · Experience: Shoichet Lab · Education: University of Toronto · Location: Toronto · 148 connections on LinkedIn. 1021 Publication Education MASc Student (2025-present) Biomedical Engineering University of Toronto Bachelor of Science (2019-2024) Biochemistry The University of British Columbia Awards Ontario Graduate Scholarship (OGS) Ellie Monroe | email | linkedin Shoichet Lab, (University of Toronto) Hometown: Langley, BC Interests: Painting, outdoors, travelling, baking, singing 51. The Shoichet lab seeks to bring chemical reagents to biology, combining computation and experiment. View Nicole Blaine, MASc’s profile on LinkedIn, a professional community of 1 billion members. Hammond Bachelor of Engineering (2012 – 2016) Chemical Engineering McGill University Awards Select Publications The lab works to find strategies to promote healing in the body that would not otherwise happen on their own, especially after traumatic injury to the brain (including stroke) or spinal cord or in degenerative diseases such as blindness. 05. She served as Ontario’s first Chief Scientist in 2018 where she worked to enhance the culture of science. Shoichet at molly [dot] shoichet [at] utoronto. A longstanding effort to do so is by exploiting protein structures to predict new reagents and therapeutic leads (structure-based ligand discovery). B. Sivak is an associate professor in Temerty Faculty of Medicine’s Department of Ophthalmology & Vision Science and the glaucoma research chair at the Krembil Research Institute, part of the University Health Network. Shoichet joined the University of Toronto in 1995, where she remains as of 2019. from the Education Ph. 2023 Publication I worked as an undergraduate research assistant at the Shoichet Lab at the University of Toronto under Timothy Cheung. 3c00029 A team of scientists led by Molly Shoichet and funded by Medicine by Design is working on a ground-breaking research project to restore vision using retinal stem cells. D. shoichet@utoronto. 1002 Publication Molly shoichet University of Toronto Verified email at utoronto. However, the engraftment Contact info Molly Shoichet Lab, Mailing Address University of Toronto Donnelly Centre for Cellular & Biomolecular Research 160 College Street, Room 530 Toronto, Ontario M5S 3E1 Canada Office Address Professor Molly S. 2019 “Induction of Rod and Cone Photoreceptor-Specific Progenitors from Tissue Engineering Technician, 06/2018-presentCopyright © 2025 - WordPress Theme by CreativeThemes Education Master of Applied Science, 2025-Present Chemical Engineering & Applied Chemistry University of Toronto Honours Bachelor of Science, 2021-2025 Chemistry Major, Immunology Minor, Astronomy & Astrophysics Minor University of Toronto Awards Ontario Graduate Scholarship (OGS) Molly Shoichet is among 4 other researchers at the University of Toronto who has been recognized with the inaugural Derrick Rossi Innovation Award UofT News Molly Shoichet is among 4 other researchers at the University of Toronto who has been recognized with the inaugural Derrick Rossi Innovation Award UofT News Professor Molly Shoichet is University Professor, a distinction held by less than 2% of the faculty, at the University of Toronto. 2024. ca The Shoichet Lab has developed a novel hyaluronan based hydrogel with properties that allow for injection into the eye. Molly co-founded AmacaThera in 2016 and is a University Professor at the University of Toronto, where her research focuses on drug and cell delivery strategies in the central nervous system (brain, spinal cord and retina) and 3D hydrogel culture systems to model cancer. Ellie Monroe | email | linkedin Shoichet Lab, (University of Toronto) Hometown: Langley, BC Interests: Painting, outdoors, travelling, baking, singing Molly Shoichet is among 4 other researchers at the University of Toronto who has been recognized with the inaugural Derrick Rossi Innovation Award UofT News 51. 202419306 Publication MONOGRAPHS, BOOKS OR BOOK CHAPTERS 35. Bachelor in Science (2018 – 2022) Honours Biology University of Wat “Engineered in vitro tumour model recapitulates molecular signatures of invasion in glioblastoma” Smith LJ; Skirzynska A; Chin AA; Arnold AE; Kushida M; Dirks P; Shoichet MS. Shoichet University of Toronto Donnelly Centre for Cellular & Biomolecular Research 160 College Street, Room 514 Toronto Toronto Star, Doctors’ Notes The Aug 8, 2016 issue of the Toronto Star features the Shoichet lab’s cell transplantation research. My project involves leveraging the specificity of protein interactions to • July/August 2015 – The Shoichet Lab welcomes the following summer students: Shermaine Li, Jay Chi, Jill Harrop, Elliot Birman, and Molly Lindway. Bio Business Magazine In the July/August 2016 issue of Bio Business Magazine, Dr. 1996 “In vivo biostability of a polymeric hollow fiber membrane for cell encapsulation” Biomaterials, 17: 285-90; doi: 10. 2024 Chemistry of Materials (special issue), 36: 614-641; doi: 10. 2024 Advanced Materials, e2403701: 1-16; doi: 10. Slaughter KV; Donders EN; Jones MS; Sabbah SG; Elliott MJ; Shoichet BK; Cescon DW; Shoichet MS. Shoichet talks about some of the stem Jul 23, 2025 · Molly Shoichet is the Canada Research Chair in Tissue Engineering. The platform — based on a type of material known as a hydrogel, a soft jelly-like substance Contact Home People Molly Shoichet The Team Former Team Members Undergraduate Research Publication “RNA lipid nanoparticles stabilized during nebulization through excipient selection” Slaughter KV; Isaacs-Bernal D; Donders EN; Wang S; Sabbah SG; Li X; Dang M; Jackiw IM; Chan KYT; Cullis PR; Shoichet MS. M. Publication Molly Shoichet joins PRiME as new scientific director for Precision Medicine Initiative PRiMEUniversity of Toronto News PRiME Next-Generation Precision Medicine A team of scientists led by Molly Shoichet and funded by Medicine by Design is working on a ground-breaking research project to restore vision using retinal stem cells. She leads a large research group at the University of Toronto that combines engineering, chemistry and biology to address some of the biggest questions in medicine, such as how to restore vision and how to regenerate the brain after stroke. ; Lu, S. Our multidisciplinary projects benefit from collaborations with scientists with complementary expertise, in stem cell biology, neurosurgery and cancer. Professor Molly Shoichet holds the Tier 1 Canada Research Chair in Tissue Engineering at the University of Toronto. Shoichet talks about the long process of turning scientific breakthroughs into clinical treatment available to patients. • June 2015 – Congratulations to Shoichet Lab Alumnus, Prof Nic Leipzig, on his recent promotion to Associate Professor with tenure at the University of Akron! Education Masters of Applied Science (2023 – 2025) Department of Chemical Engineering and Applied Chemistry University of Toronto Bachelor of Science Honours Bio-Organic Chemistry McGill University Awards Professor Doug Reeve Engineering Leaders of Tomorrow Graduate Award (2023) Education Post-Doctoral Fellow (2021 – Present) Department of Chemical Engineering University of Toronto Supervisor: Molly Shoichet Doctor of Philosophy (2016 – 2021) Department of Chemistry University of Western Ontario Supervisor: Elizabeth Gillies Bachelor of Science (2010 – 2014) Chemical Biology Thompson Rivers University Education Bachelor of Arts, English Specialization University of Toronto Interests Cooking, working out, and my favourite is, of course, playing with my baby girl 148. ; Ho, E. 2021 “Wielding the double-edged sword of inflammation: building biomaterial-based strategies for immunomodulation in ischemic stroke treatment”, Advanced Functional Materials, special issue on Advanced Materials for Drug Delivery and Theranostics. Margolese National Brain Disorders Prize Professor Molly Shoichet receives Margolese National Brain Disorders Prize Chem Eng News. ; Shoichet, M. To avoid this, cancel and sign in to YouTube on your computer. biomaterials. S. 2025 Advanced Materials, 37: 2419306: 1-14; doi: 10. chemmater. In a protein-centric approach, molecular docking, we discover new ligands that complement protein structures. 2025 Nanoscale Advances (special issue), 7: 4480-4489; doi: 10. Candidate (2022 – Present) Biomedical Engineering University of Toronto Bachelor of Applied Science (2017 – 2022) Civil Engineering University of Alberta Molly Shoichet is among 4 other researchers at the University of Toronto who has been recognized with the inaugural Derrick… Accepting students for 4-month summer research positions, full year PEY (co-op), and undergraduate thesis students If you are interested in joining our research group, please forward a copy of your CV/resume and transcript to Dr. 2024, Biomaterials, 314: 122818; doi: 10. 2024, Acta Biomaterialia, 181: 117-132; doi: 10. 001 Publication INTERNATIONAL AWARDS Fellow, National Academy of Inventors, 2023 New College of Fellows, Controlled Release Society, 2021 Fellow, The Royal Society, 2019 Controlled Release Society, Women in Sciences Award, 2019 IUPAC 2019 Distinguished Women in Chemistry or Chemical Engineering – one of ten women identified internationally and only woman from Canada Foreign Member, United States National Contact Home People Molly Shoichet The Team Former Team Members Undergraduate Research L. She is the Michael E Charles Professor in Chemical Engineering and held the Tier 1 Canada Research Chair in Tissue Engineering (2001-2020). Shoichet has published over 650 papers, patents and abstracts and has given over 420 lectures worldwide. Developing new computational methods for ligand discovery and 2. However, therapeutic delivery to the retina can be challenging: topical applications are limited by rapid drug clearance and bolus intravitreal injections by risk of overdose, inflammation, and cataracts. 2024, Advanced Functional Materials, 2413220; doi: 10. 1039/d4na01034e Publication Cheung TH; Shoichet MS. ca tegic design to Yuan Yao Post-Doctoral Fellow, 09/2022 - PresentSiewan Prev 1 2 3 4 5 … 7 Next A Biomanufacturing Hub Network (BioHubNet) team led by U of T University Professor Molly Shoichet and Scientific Director of PRiME Next-Generation Precision Medicine, along with co-leads Gilbert Walker, Professor of Chemistry at U of T, and Darius Rackus, Assistant Professor of Chemistry and Biology at Toronto Metropolitan University, has been awarded $18. I will leverage my experience in protein chemistry and biophysics to engineer this hydrogel to stabilize and control the release of protein-based regenerative therapeutics. 1021/acs. Ivan Zlotver Post-Doctoral Fellow 07/2024 – 02/2025 Currently Project Myocardial ischemia occurs due to the progression of atherosclerotic plaque in coronary artery. Allysia Chin PhD Candidate, 09/2024 - Present Siewan Uncategorized Nitzan Letko Khait Research Associate, 07/2025 - Present Siewan Prev 1 … 4 5 6 7 Molly Shoichet Named Ontario’s First Chief Scientist Congratulations to Molly Shoichet! On Friday November 17, 2017, Molly Shoichet is named Ontario’s first Chief Scientist. 8k 1k xymj6q prsjd gvdri1 oki zmf 1m t03aj iigeh